Design, synthesis, purification and analysis of ASO. si. RNA and/or its conjugates to small molecules, Peptides, Dyes and Antibodies. Ability to operate Mermade 12 and Akta Synth synthesizers using Phosphoramidite chemistry. Solid phase synthesis of oligonucleotides at medium scales (20 mg -1.0 g),Large Scale Purification and Ultrafiltration of oligonucleotides by anion-exchange and reverse-phase HPLC systems,Deep understanding of oligonucleotide and precursor synthesis, purification, and familiarity with analytical methods in oligonucleotide drug development. Demonstrate an ability to work as part of a team and possess an excellent work ethic. Present funding in team meetings. Maintain a well-documented laboratory notebook and follow the safe laboratory practices. Multi-task across several projects and manage time effectively to achieve results. Who You Are Minimum Qualifications:PhD in Chemistry, science or engineering . years of direct experience in oligonucleotide chemistry. Preferred Qualifications:Strong knowledge of Oligonucleotide Synthesis, Deprotection and Purification techniques. Knowledge and background in bioconjugation chemistry including antibody-drug conjugates and related linkers. Experience in conjugation/bioconjugation chemistry. Solid-phase synthesis techniques with oligonucleotides or peptides. Expertise in chromatography purification techniques and troubleshooting. Strong laboratory skills and experience with analytical instrumentation such as NMR, HPLC, LC-MS, etc. with the ability to analyze, interpret, and clearly present data. Pay Range for this position: $111,100-$166,600.